Huntingtons+Disease

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The Huntington's Disease was first dicovered in 1872 by an American doctor named George Huntington. Huntington's disease is caused when chromosome #4 is genetically defected. This defect causes part of the chromosome's DNA called CAG to repeat more times then it is supposed to repeat. A normal section of this chromosome will repeat generally between 10 to 35 times, while the defected chromosome will repeat itself between 36 to 120 times. As this is passed down from generation to generation the number of times the section repeats will become larger and larger. The greater amount of repeating, the greater chance of the ofspring developing the disease at an early age. As said before, Huntingtons Disease is an autosomal and since it is inherited, everyone in the family who has this faulty gene will most likely pass it on to offspring. A parent who has this disease if 50% likely to pass it on. =====

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Most symptoms for Huntingtons Diseas will appear between the ages of 30 and 50 or earlier but, for children they can appear at any time. Some symptoms can include poor memory, lack of coordination, difficulty walking, speaking, and or swallowing, twitching or other uncontrolled movements, and depression and or mood swings. As the diseas progresses into the later stages a person would need help doing the most simplest of tasks such as getting dressed. Some behavioral changes such as antisocial behaviors, irritability, moodiness, hallucinations, paranoia, psychosis, and restlessness or fidgeting may occur before any movement problems arise. When a person starts to experience wild and radical movements, their head may start to turn to shift eye position, they may have slow, uncontrolled movements, their facial movements may include grimaces, they may have quick, sudden, and sometimes wild jerking movements in the arms, face, legs, or other body parts.

So far there are no treatment options for Huntington's Disease. No one knows of any way to stop it from getting worse. One goal for treatment would be to slow down the disease from killing the patient and allowing them to live a longer life. There is hope however. Some medication can be given to a person with the disease to allow them to live a more normal life. Medicine like dopamine blockers and haloperidol, tetrabenazine, and amantadine drugs can be administered to help reduce abnormal behaviors and movements and to control any extra movements of the body.

Information about treatment options visit http://dockgenetics.wikispaces.com/Huntington's+Disease-+Eleah+Weber