Q: What is cystic fibrosis?
A: Cystic fibrosis is an inherited disease that causes thick, sticky mucus to build up in the lungs and digestive tract. It is one of the most common chronic lung diseases in children and young adults, and may result in early death.

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Q: How is cystic fibrosis formed?
A: Cystic fibrosis is formed by a gene defect that can either be caused from a mutation, or can be passed down through genetics

Q:How common is cystic fibrosis?
A: About 1 in 29 americans have cystic fibrosis

Q: How early can cystic fibrosis be detected?
A: Most people with cystic fibrosis are diagnosed by the age of 2.

the Cystic fibrosis affects more than 30,000 kids and young adults in the United States.

Respiratory System Signs and Symptoms
Digestive System Signs and Symptoms
Nasal Polyps - Inflamed tissue lining in the nose
Abdominal pain
Pneumothorax - The presence of air or gas in the plural cavity causing the
lung to collapse
Gas in the intestines
Hemoptysis- Coughing up blood
Liver disease
collapsed lung
reccurent Pneumonia
Frequent flatulence
excessive salt in sweat
enlarged fingertips (clubbing)
Chronic sinustis
failure to pass on stool
CF causes you to sweat. As a result of this, your body loses large amounts of salt when you sweat. This can cause dehydration (a condition in which your body doesn't have enough fluids), higher heart rate, tiredness, weakness, decreased blood pressure, heat stroke, and, sometimes can cause death.


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Doctors may think a baby has CF if he or she coughs a lot and gets a lot of lung infections.The baby also might have unusually large bowel movements or not gain weight as expected.

A blood test can also be used to see if the sample has the CF gene. Another way of diagnosing cystic fibrosis is through a test called the sweat test. Doctors will take a sample of the subjects sweat, and measure its salt levels. If high levels of salt are detected, a diagnosis for cystic fibrosis is confirmed. Sweat tests are the most useful for diagnosing cystic fibrosis.

To make a diagnosis on an unborn babies, a fluid sample is taken from the uterus, and tested to see if its CTFR genes are normal, or if the child has cystic fibrosis.


There currently is no cure for cystic fibrosis, but there are treatments that can ease symptoms and reduce complications.
Medications used are :
  • Antibiotics. drugs that are used to treat and help prevent lung infections.
  • Mucus-thinning drugs. Drugs that reduce the stickiness of your mucus make it easier to cough up the mucus, improving lung functions.
  • Bronchodilators. an inhaler or a nebulizer to help keep your airways open by relaxing the muscles around your bronchial tubes.

Therapies :

People with cystic fibrosis need to physically remove mucus from their lungs. This is often done by clapping with cupped hands on the front and back of the chest Best performed with the person's head over the edge of a bed so that gravity helps clear the lungs.

  • Chest clapper. This hand-held device can mimic the effect of cupped hands clapping over the ribs.
  • Inflatable vest. This device vibrates at high frequency help to loosen the mucus in the lungs
  • Breathing devices. specific breathing exercises while exhaling through the device's tube or a mask may also help get rid of mucus in the lungs.


Cystic fibrosis is caused by a mutation in a gene. Cystic fibrosis is a hereditary disease that can be passed on only if both his or her parents both are carriers or have cystic fibrosis. A child must inherit two copies of the defective gene in order to have the disorder CF. People with this disorder, the gene does not work effectively. This causes thick sticky mucus and very salty sweat.

The gene controls the protein that controls the movement of salt, and water throughout the cells. People with the faulty gene make bad proteins, that don't to their job leading to sticky mucus, and salty sweat. There are many defects that can happen with the CTFR gene, different defects can have different severities of the condition.

Carrying CF have no signs of cystic fibrosis. They can live normal lives. The only risk they have is passing the gene down to their offspring. An offspring of 2 carriers has a 1/4 chance of having cystic fibrosis.



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The first clear description of Cystic Fibrosis was in 1938 by doctor named Dr Dorothy Andersen. While preforming an autopsy of someone who supposedly died of celiac disease, she came upon the discovery of cystic fibrosis.
Cystic fibrosis has been known for more than 50 years that cystic fibrosis is an autosomal (not a sex linked) genetic disease.The reason for this disease is be
cause of a genetic mutation that occurs in the Cystic Fibrosis Transmembrane Conductance Regulator, also called the CFTR gene.
Many medical researchers believe that the original mutation may have happened fifty-two thousand years ago.
Cystic fibrosis was recognized as an actual disease within the past century. Between 50,000 B.C. and the now, a mutation occurred in the CFTR gene. There have been lung infections, heart failure, and pancreas diseases for many years , but cystic fibrosis wasn't being viewed as a cause took until 1938. 1943 – While in cystic fibrosis was gaining recognition in 1938, it was not until 1943 that it was considered a legitimate disease.

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